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A "leukemic or blastoid phase" is a finding of unusual high amounts of lymphocytes in the peripheral blood (lymphocytosis) suggesting that the lymphoma cells are in the blood in high concentrations.
lymphocytosis is an abnormal increase in the number of lymphocytes — a type of white blood cell — in your blood. The most common cause is viral infection, such as EBV, CMV, rubella, whooping cough, toxoplasmosis, brucellosis, chronic lymphatic leukaemiam, and leukemic phase lymphoma.
It's our impression that special attention must be paid to tumor lysis syndrome when treating lymphoma in the leukemic phase - because the tumor cells may respond very rapidly to treatment, stressing the body to eliminate the cells killed (lysis) by therapy.
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This report presents a rare case of long-term survivor of MCL with a progression of the original MCL cell clone to MCL-BV and demonstrates the clinical value of quantitative minimal residual disease assessment for optimized therapeutic management.
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