When the kidneys are not working well, the waste products normally eliminated by the kidneys will be elevated in the blood.
During treatment, markers of kidney toxicity can be expected and may get better with time. Your doctor will measure concentrations of the waste substances in your blood and urine to monitor renal function:
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Certain chemotherapy drugs
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Radiation therapy - Dr. Eric Cohen: Radiation Nephropathy http://bit.ly/11tQgm3
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Some biologic therapies, such as interferon
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Intravenous (IV) contrast for imaging
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Blockage of blood flow to or from the kidney - by kidney stones or a tumor.
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Low blood pressure or irregular heart rhythms
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Being dehydrated
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Diuretics drugs
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Urinary infection, or inflammation of one or more of your kidneys
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Some antibiotics
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Heart disease and some drugs to treat heart conditions
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NSAID drugs
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Enlarged prostate gland
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Gastrointestinal tract or stomach bleeds (GI bleed).
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Too much protein in your diet
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Low blood pressure
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Diabetes
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A blockage of blood flow to or from the kidney. This may be caused by kidney stones or a tumor.
Can kidney stones cause kidney failure or damage? - KidneyStoners.org http://bit.ly/1vdJqyg
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Irregular heart rhythms can blood flow to the kidneys producing signs of kidney problems.
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Abnormally dark or light skin
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Bone pain
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Drowsiness or problems concentrating or thinking
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Numbness or swelling in the hands and feet
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Muscle twitching or cramps
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Breath odor
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Easy bruising, or blood in the stool
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Excessive thirst
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Frequent hiccups
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Problems with sexual function
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Menstrual periods stop (amenorrhea)
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Shortness of breath
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Sleep problems
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Vomiting, often in the morning
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Kidney involvement in leukemia and lymphoma. - PubMed - NCBI http://1.usa.gov/1A7Rv9z
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Acute kidney injury in the cancer patient. - PubMed - NCBI http://1.usa.gov/1uyIpQe
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Chemocare: Nephrotoxicity (Renal Toxicity) - Managing Side Effects - http://bit.ly/1q0h9tL
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Chronic Kidney Disease: Prevention and Treatment of Common Complications
http://www.aafp.org/afp/2004/1115/p1921.html
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WebMD: Urine Test http://bit.ly/1sYUzNO
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Tests commonly used for screening, diagnosis, and monitoring:
Source: Lab Tests Online http://labtestsonline.org/understanding/conditions/kidney/start/3
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Chronic kidney disease: MedlinePlus Medical Encyclopedia http://1.usa.gov/1pRELRc
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Chemocare.com: About Nephrotoxicity (Renal Toxicity)
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NIH: About Kidney function and disease http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/
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How to prevent, recognize, and treat drug-induced kidney toxicity - nephrotoxicity ~ - ccjm.org PDF
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Anticancer drug-induced kidney disorders.
Drug Saf. 2001 Jan;24(1):19-38. Review. PMID: 11219485
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Nephrotoxicity from chemotherapy: prevention and management.
Oncology (Huntingt). 1991 Oct;5(10):97-102, 105; disc. 105, 109-11. Review. PMID: 1838278
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Cisplatin Nephrotoxicity: A Review
http://medicine-opera.com/wp-content/uploads/2008/05/cisplatin-nephrotoxicity.pdf
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