Last update: 02/14/2006

We encourage patients who are already in need of biopsy to go to centers that are participating in the Cooperative Human Tissue Network (CHTN) or related programs.  Also see NBN.

The CHTN has provided specimens needed for the development of emerging technologies and the application of these technologies to study problems in cancer biology, and to develop markers for diagnosis, prognosis and prediction of response to therapy. In recent years, the CHTN has supported a wide spectrum of oncogenomic studies including:

	Characterization of epigenetic lesions as non-random and tumor specific type events.
	Studies of gene expression profiles and studies to determine the clinical usefulness of such profiles.
	Identification of novel diagnostic molecular markers by exploiting genome wide expression tools.
	Methylation microarray analysis of cancers

The CHTN was formed in 1987 by three organizations along with a subcontract with the Children's Cancer Group (CCG). In 1991 the Pediatric Division became an independent group and an additional adult collection center was added to the CHTN. 

For Researchers:  Contact: Kim Jessup, M.D., NCI Cancer Diagnosis Program at (301)435-9010,

All six organizations that currently comprise the CHTN have extensive experience in providing human tissues for research.  Alternatively, patients treated in NCI-designated Cancer Centers are likely to find physicians who will be glad to help with tissue donation. 

The Ohio State University (OSU) has had an internal tissue procurement service sponsored by their Comprehensive Cancer Center since 1975 and it joined the CHTN in 1987. Daniel Sedmak, M.D., is the principal investigator for this Midwestern Division of the CHTN.
phone: 614-293-6906
fax: 614-293-5851

The Pediatric Division, located at Children's Hospital of Columbus under the direction of Stephen J. Qualman, M.D., obtains most of its specimens through Children's Oncology Group institutions. Sixty percent of all pediatric cancer patients in the United States are treated at C.O.G. institutions.
phone: 614-722-2714
fax: 614-722-2897

The University of Alabama at Birmingham's (UAB) Tissue Procurement Facility has supplied fresh and snap-frozen human tissues to investigators within and outside their Comprehensive Cancer Center since 1978. UAB joined the CHTN in 1987. William E. Grizzle, M.D., Ph.D., the principal investigator for this Southern Division of the CHTN, is a board-certified clinical and anatomic pathologist as well as a funded medical researcher.
phone: 205-934-6071
fax: 205-934-0816

The University of Pennsylvania (UPENN) serves as the Eastern Division of the CHTN under the direction of Principal Investigator, Dr. Virginia LiVolsi, Professor of Pathology and Laboratory Medicine, who has served as the Eastern Division P.I. since the inception of the CHTN. During that time, the Eastern Division has expanded its tissue procurement network to include numerous hospitals in the Eastern region. 
phone: 215-662-4570
fax: 215-614-0251

The University of Virginia has had a tissue procurement service since 1993. It served the NCI as a major tissue supplier for the Cancer Genome Anatomy Project. Dr. Christopher Moskaluk, Assistant Professor of Pathology, serves as the Principal Investigator of the Mid-Atlantic Division.
phone: 434-924-9879
fax: 434-924-9438

Vanderbilt University's Tissue Procurement Facility operated as a subcontract tissue procurement site for the CHTN for six years before becoming the Western Division of the CHTN in 2001. Dr. Mary Kay Washington, Professor of Pathology, is currently the Principal Investigator of the Western Division.
phone: 615-322-7486
fax: 615-322-4741

Contact information:
http://www-chtn.ims.nci.nih.gov/contacts.html#ED 

Other Centers that will cooperate with this program on patient request:

NCI-designated cancer centers - Cancer.gov (in state order. Scroll down to list)

NCI-designated Cancer Centers** (° denotes facilities that are strictly laboratories and 
do not provide patient services) and Comprehensive* Cancer Centers Supported by NCI

Information about referral procedures, treatment costs, and services available to patients can be obtained by contacting the individual cancer centers listed below.

ALABAMA	University of Alabama at Birmingham Comprehensive Cancer Center*
	Address:	1824 Sixth Avenue South Birmingham, AL 35294–3300
	Telephone:	205–975–8222 1–800–822–0933 (1–800–UAB–0933)
	Internet Web site:	http://www3.ccc.uab.edu/
ARIZONA	Arizona Cancer Center*
	Address:	The University of Arizona 1515 North Campbell Avenue Post Office Box 245024 Tucson, AZ  85724
	Telephone:	520–626–2900 (New Patient Registration Line) 1–800–622–2673 (1–800–622–COPE)
	Internet Web site:	http://www.azcc.arizona.edu/
	E-mail:	copeline@azcc.arizona.edu
	Mayo Clinic Cancer Center—Scottsdale*
	Address:	13400 East Shea Boulevard Scottsdale, AZ 85259
	Telephone:	480–301–8484 or 480–301–1735 (Appointment Office)
	Internet Web site:	http://www.mayoclinic.org/cancercenter/
CALIFORNIA	The Burnham Institute**°
	Address:	10901 North Torrey Pines Road La Jolla, CA 92037
	Telephone:	858–646–3100
	Internet Web site:	http://www.burnhaminstitute.org/
	Chao Family Comprehensive Cancer Center*
	Address:	University of California, Irvine Building 23, Route 81 101 The City Drive Orange, CA 92868
	Telephone:	714–456–8200
	Internet Web site:	http://www.ucihs.uci.edu/cancer/
	City of Hope*
	Address:	Cancer Center and Beckman Research Institute 1500 East Duarte Road Duarte, CA 91010–3000
	Telephone:	626–256–4673 (626–256–HOPE) 1–800–826–4673 (1–800–826–HOPE)
	Internet Web site:	http://www.cityofhope.org/
	E-mail:	becomingapatient@coh.org
	Jonsson Comprehensive Cancer Center at UCLA*
	Address:	8–684 Factor Building UCLA Box 951781 Los Angeles, CA 90095–1781
	Telephone:	310–825–5268
	Internet Web site:	http://www.cancer.mednet.ucla.edu/
	E-mail:	jcccinfo@mednet.ucla.edu
	UC Davis Cancer Center**
	Address:	University of California, Davis 4501 X Street Sacramento, CA 95817
	Telephone:	1–800–362–5566 (Patient Referral) 916–734–5900
	Internet Web site:	http://cancer.ucdmc.ucdavis.edu/
	Rebecca and John Moores University of California, San Diego Cancer Center*
	Address:	9500 Gilman Drive La Jolla, CA 92093–0658
	Telephone:	858–534–7600
	Internet Web site:	http://cancer.ucsd.edu
	The Salk Institute for Biological Studies** °
	Address:	Post Office Box 85800 10010 North Torrey Pines Road La Jolla, CA 92037
	Telephone:	858–453–4100
	Internet Web site:	http://www.salk.edu/
	University of California, San Francisco Comprehensive Cancer Center*
	Address:	Box 0128, UCSF 1600 Divisadero Street San Francisco, CA 94143–0128
	Telephone:	1–800–888–8664 (Cancer referral line)
	Internet Web site:	http://cc.ucsf.edu/
	E-mail:	referral.center@ucsfmedicalcenter.org
	USC/Norris Comprehensive Cancer Center and Hospital*
	Address:	1441 Eastlake Avenue Los Angeles, CA 90033–0804
	Telephone:	323–865–3000 1–800–872–2273 (1–800–USC–CARE)
	Internet Web site:	http://ccnt.hsc.usc.edu/
	E-mail:	cainfo@ccnt.hsc.usc.edu (For general information)
COLORADO	University of Colorado Cancer Center*
	Address:	Anschutz Cancer Pavilion Box F–704 1665 North Ursula Street Aurora, CO 80010
	Telephone:	720–848–0300 1–800–473–2288 (Cancer referral line)
	Internet Web site:	http://www.uccc.info/
CONNECTICUT	Yale Cancer Center*
	Address:	Yale University School of Medicine 333 Cedar Street Post Office Box 208028 New Haven, CT 06520–8028
	Telephone:	203–785–4095 (Administrative Offices)
	Internet Web site:	http://www.info.med.yale.edu/ycc/
DISTRICT OF COLUMBIA	Lombardi Comprehensive Cancer Center*
	Address:	Georgetown University Medical Center 3800 Reservoir Road, NW. Washington, DC 20057
	Telephone:	202–444–4000
	Internet Web site:	http://lombardi.georgetown.edu/
FLORIDA	H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida*
	Address:	12902 Magnolia Drive Tampa, FL 33612–9497
	Telephone:	813–972–4673 (813–972–HOPE) 1–800–456–3434
	Internet Web site:	http://www.moffitt.usf.edu/
	Mayo Clinic Cancer Center—Jacksonville*
	Address:	4500 San Pablo Road Jacksonville, FL 32224
	Telephone:	904–953–2272 904–953–2300 (TTD hearing-impaired line)
	Internet Web site:	http://www.mayoclinic.org/cancercenter/
HAWAII	Cancer Research Center of Hawaii**
	Address:	1236 Lauhala Street Honolulu, HI 96813
	Telephone:	808–586–3010
	Internet Web site:	http://www.crch.org
ILLINOIS	The Robert H. Lurie Comprehensive Cancer Center*
	Address:	Northwestern University Olson Pavilion 8250 303 East Chicago Avenue   Chicago, IL 60611
	Telephone:	312–908–5250 1–866–587–4322 (1–866–LURIE–CC) (Appointment Line)
	Internet Web site:	http://cancer.northwestern.edu/home/index.cfm
	E-mail:	cancer@northwestern.edu
	University of Chicago Cancer Research Center**
	Address:	Mail Code 2115 5841 South Maryland Avenue Chicago, IL 60637–1470
	Telephone:	773–702–9200 1–888–824–0200 (For new patients)
	Internet Web site:	http://uccrc.uchicago.edu/current/home.html
INDIANA	Indiana University Cancer Center**
	Address:	535 Barnhill Drive Indianapolis, IN 46202–5289
	Telephone:	317–278–4822 1–888–600–4822
	Internet Web site:	http://iucc.iu.edu
	Purdue Cancer Center** °
	Address:	Hansen Life Sciences Research Building Purdue University 201 South University Street West Lafayette, IN 47907–2064
	Telephone:	765–494–9129
	Internet Web site:	http://www.cancer.purdue.edu/
IOWA	The Holden Comprehensive Cancer Center at The University of Iowa*
	Address:	Room 5970–Z JPP 200 Hawkins Drive Iowa City, IA 52242–1009
	Telephone:	1–800–777–8442 (Patient referral) 1–800–237–1225 (For general information)
	Internet Web site:	http://www.uihealthcare.com/depts/cancercenter/
	E-mail:	Cancer-Center@uiowa.edu
MAINE	The Jackson Laboratory** °
	Address:	600 Main Street Bar Harbor, ME 04609–0800
	Telephone:	207–288–6000 (main) 207–288–6051 (public information)
	Internet Web site:	http://www.jax.org/
	E-mail:	pubinfo@jax.org
MARYLAND	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins*
	Address:	The Harry and Jeanette Weinberg Building Suite 1100 401 North Broadway Baltimore, MD 21231–2410
	Telephone:	410–955–8964 (Patient referral) 410–955–8804 (Clinical trials)
	Internet Web site:	http://www.hopkinskimmelcancercenter.org
MASSACHUSETTS	Dana-Farber Cancer Institute*
	Address:	44 Binney Street Boston, MA 02115
	Telephone:	1–866–408–3324 (1–866–408–DFCI)
	Internet Web site:	http://www.dana-farber.org/
	MIT Center for Cancer Research** °
	Address:	Room E17–110 Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge, MA 02139–4307
	Telephone:	617–253–8511
	Internet Web site:	http://web.mit.edu/ccr/index.html
MICHIGAN	Barbara Ann Karmanos Cancer Institute* Operating the Meyer L. Prentis Comprehensive Cancer Center of Metropolitan Detroit
	Address:	Wertz Clinical Cancer Center 4100 John R Street Detroit, MI 48201–1379
	Telephone:	1–800–527–6266 (1–800–KARMANOS)
	Internet Web site:	http://www.karmanos.org/
	E-mail:	info@karmanos.org
	University of Michigan Comprehensive Cancer Center*
	Address:	1500 East Medical Center Drive Ann Arbor, MI 48109–0944
	Telephone:	1–800–865–1125 (Cancer Answer Line)
	Internet Web site:	http://www.cancer.med.umich.edu/
	E-mail:	wwwcancer@umich.edu
MINNESOTA	Mayo Clinic Cancer Center*
	Address:	200 First Street, SW. Rochester, MN 55905
	Telephone:	507–284–2111 (Central Appointment Office)
	Internet Web site:	http://www.mayoclinic.org/cancercenter/
	University of Minnesota Cancer Center*
	Address:	Mayo Mail Code 806 420 Delaware Street, SE. Minneapolis, MN 55455
	Telephone:	612–624–8484
	Internet Web site:	http://www.cancer.umn.edu/
	E-mail:	info@cancer.umn.edu
MISSOURI	Siteman Cancer Center*
	Address:	Barnes-Jewish Hospital and  Washington University School of Medicine Box 8100 660 South Euclid Avenue St. Louis, MO 63110–1093
	Telephone:	314–747–7222 1–800–600–3606
	Internet Web site:	http://www.siteman.wustl.edu/
NEBRASKA	UNMC Eppley Cancer Center**
	Address:	University of Nebraska Medical Center 986805 Nebraska Medical Center Omaha, NE 68198–6805
	Telephone:	402–559–4238
	Internet Web site:	http://www.unmc.edu/cancercenter/
NEW HAMPSHIRE	Norris Cotton Cancer Center*
	Address:	Dartmouth-Hitchcock Medical Center One Medical Center Drive Lebanon, NH 03756–0002
	Telephone:	603–653–9000 (Administration) 1–800–639–6918 (Cancer Help Line)
	Internet Web site:	http://www.cancer.dartmouth.edu/index.shtml
	E-mail:	cancerhelp@dartmouth.edu
NEW JERSEY	The Cancer Institute of New Jersey*
	Address:	195 Little Albany Street New Brunswick, NJ 08903–2681
	Telephone:	732–235–2465 (732–235–CINJ)
	Internet Web site:	http://www.cinj.org
NEW YORK	Albert Einstein Cancer Center**
	Address:	Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, NY 10461
	Telephone:	718–430–2302
	Internet Web site:	http://www.aecom.yu.edu/cancer
	E-mail:	aeccc@aecom.yu.edu
	Cold Spring Harbor Laboratory**°
	Address:	Post Office Box 100 1 Bungtown Road Cold Spring Harbor, NY 11724
	Telephone:	516–367–8397
	Internet Web site:	http://www.cshl.org/
	Herbert Irving Comprehensive Cancer Center*
	Address:	New York-Presbyterian Hospital Columbia University Medical Center PH 18, Room 200 622 West 168th Street New York, NY 10032
	Telephone:	1–877–697–9355 (1–877–NYP–WELL) 1–800–227–2762 (Physician Referral)
	Internet Web site:	http://www.ccc.columbia.edu/
	Memorial Sloan-Kettering Cancer Center*
	Address:	1275 York Avenue New York, NY 10021
	Telephone:	1–800–525–2225
	Internet Web site:	http://www.mskcc.org/
	NYU Cancer Institute**
	Address:	New York University Cancer Institute 550 First Avenue New York, NY 10016
	Telephone:	212–263–6485
	Internet Web site:	http://www.nyucancerinstitute.org
	Roswell Park Cancer Institute*
	Address:	Elm and Carlton Streets Buffalo, NY 14263–0001
	Telephone:	1–800–767–9355 (1–800–ROSWELL)
	Internet Web site:	http://www.roswellpark.org/
NORTH CAROLINA	Comprehensive Cancer Center of Wake Forest University*
	Address:	Wake Forest University Baptist Medical Center Medical Center Boulevard Winston-Salem, NC 27157–1082
	Telephone:	336–716–4464
	Internet Web site:	http://www1.wfubmc.edu/cancer
	Duke Comprehensive Cancer Center*
	Address:	Duke University Medical Center Box 3843 301 MSRB Durham, NC 27710
	Telephone:	919–684–3377 1–888–275–3853 (1–888–ASK–DUKE) (Consulation and Referral Center)
	Internet Web site:	http://www.cancer.duke.edu
	UNC Lineberger Comprehensive Cancer Center*
	Address:	School of Medicine  University of North Carolina at Chapel Hill Campus Box 7295 Chapel Hill, NC 27599–7295
	Telephone:	919–966–3036
	Internet Web site:	http://cancer.med.unc.edu/
	E-mail:	dgs@med.unc.edu
OHIO	Ireland Cancer Center*
	Address:	University Hospitals HealthSystem 11100 Euclid Avenue Cleveland, OH 44106–5065
	Telephone:	216–844–5432 1–800–641–2422
	Internet Web site:	http://www.irelandcancercenter.org
	The Ohio State University Comprehensive Cancer Center*
	Address:	The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Suite 519 300 West 10th Avenue Columbus, OH 43210–1240
	Telephone:	1–800–293–5066 (The James Line)
	Internet Web site:	http://www.jamesline.com
	E-mail:	cancerinfo@jamesline.com
OREGON	OHSU Cancer Institute**
	Address:	The Oregon Health Sciences University Cancer Institute CR145 3181 Southwest Sam Jackson Park Road Portland, OR 97239–3098
	Telephone:	503–494–1617 1–800–494–1234
	Internet Web site:	http://www.ohsucancer.com/
	E-mail:	cancer@ohsu.edu
PENNSYLVANIA	Abramson Cancer Center of the University of Pennsylvania*
	Address:	15th Floor, Penn Tower 3400 Spruce Street Philadelphia, PA 19104–4283
	Telephone:	215–662–4000 (Main number) 1–800–789–7366 (Referral and to schedule an appointment) (1–800–789–PENN)
	Internet Web site:	http://www.penncancer.org
	Fox Chase Cancer Center*
	Address:	333 Cottman Avenue Philadelphia, PA 19111–2497
	Telephone:	215–728–2570 (To schedule an appointment) 1–888–369–2427 (1–888–FOX CHASE)
	Internet Web site: