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Quality of Life

  

Treatments > Quality of Life

Last update: 03/16/2008

Quality of Life

Interventions that may improve quality of life
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Here we will compile information pertaining to  improving the quality of life of patients with NHL and other cancers. 

"It is possible that a larger and larger frequency of patients will successfully be rescued by the newer techniques over the next ten years. More and more people will die of something else besides lymphoma or the iatrogenic results of lymphoma treatment.  

This is especially true in the case of older indolent NHL patients if median survival edges up from 7-12 years (or 12-17 years in major medical centers) towards 15-20 years.  While a cure may not be at hand survival may be or may become a lesser value in evaluating a treatment than the quality of life resulting from the treatment." - David F. PhD

An Evaluation of Age-related Differences in Quality of Life Preferences in Patients with Non-Hodgkin's Lymphoma. Leuk Lymphoma. 2004 Dec;45(12):2471-6  PMID: 15621762 
Resources and Research News
Quality of life among long-term non-Hodgkin lymphoma survivors: a population-based study.
Cancer. 2007 Mar 1  PMID: 17330853 

From 5 to 15 years after diagnosis, the general health perceptions and vitality levels of non-Hodgkin lymphoma survivors remained significantly lower than those of their peers in the of general population. In addition, survivors faced practical problems with work and finances that deserve additional attention during the period of rehabilitation.
Study Finds Overall Health and Quality of Life Intact 10 Years After Stem-Cell Transplantation  prnewswire.com 
Preliminary evidence of relationship between genetic markers and oncology patient quality of life (QOL)  ASCO Highlights 

"Is there a relationship between the state of cancer patients' genetic structure and their quality of life? Genetic variants have been associated with patient toxicity or clinical outcome. There has been little work done exploring the relationship between genetic variants and patient QOL."
See NHL in elderly patients
See Liposomal Chemotherapy agents
First-line treatment with brief-duration chemotherapy plus rituximab in elderly patients with intermediate-grade non-Hodgkin's lymphoma: phase II trial. Clin Lymphoma. 2003 Jun; 4(1): 36-42  PMID: 12837153
ASH 2002:  Quality of Life is Significantly Better with Polyethylene Glycol Interferon than with the Standard Formulation  PeerviewPress.com
Tools for Evaluating 
Quality of Life (QOL)
 Quality of life as an endpoint in clinical research is difficult to measure. But tools are available that can help, and we believe the patient community is served by research that takes side effects and other quality of life factors into account.
 
Assessing quality of life in research and clinical practice. Oncology (Huntingt).  2002 Sep;16(9 Suppl 10):133-9. Review  PMID: 12380963 | Abstracts
Quality of Life Assessment in Clinical Trials  PPT
 
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