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Side EffectsNausea

Last update: 11/06/2015

TOPICS
Nausea | Quick Reference | ResourcesResearch News

Nausea is a common side effect of chemotherapy.  It may start within one to four hours following chemotherapy; the worst time is typically during the first 12 to 24 hours.

Not all chemotherapy drugs will cause nausea.

If the drugs you receive are likely to cause significant nausea, you will be given drugs for prevention prior to chemotherapy. 

"One of the tricks to dealing with these "big" meds is to prepare anti-nausea plans before-hand, and not start them when one finally does feel nauseated. 
 
My anti-nausea meds were started before I got ICE, and continued until I left the hospital, with a Rx to take home with me." ~ D

In the News

bullet Nov 2015: 
NEPA
Added to ASCO Guidelines on Antiemetic (anti-nausea) Use http://wb.md/1HwV0Xj
 
bullet Support Care Cancer. 2012 July; 20(7): 14791489. Ginger Eases Nausea From Chemo PubMed 

Ginger supplementation at daily dose of 0.5g-1.0g significantly aids in reduction of the severity of acute chemotherapy-induced nausea in adult cancer patients.

Note:
All patients also received a 5-HT3 receptor antagonist antiemetic on Day 1 of all cycles.

Drugs commonly used to control nausea (antiemetics)

Topic search for drugs that treat nausea  PubMed

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Compazine (Prochlorperazine)   MedlinePlus 
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Granisetron  nejm.org 
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Kytril (Granisetron)   MedlinePlus
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Clopra; Maxolon; Octamide; Reglan (Metoclopramide)  MedlinePlus 
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Zofran (Ondansetron)  MedlinePlus 
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Search of: Nausea - List Results - ClinicalTrials.gov http://1.usa.gov/18pA4SF

Important: If one drug does not control your nausea, do inform your doctor and request a change of medication - it can make a dramatic difference.

Tips to help prevent or control nausea

Also see Safe Shopping List for Managing Nausea

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Eat only light meals before treatment and avoid eating for at least a few hours before treatment if nausea.

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Ask your doctor about newer medication that can control nausea, such as Zofran, Emend and Kytril.

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Avoid odors that offend you.

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Avoid wearing tight or uncomfortable clothing.

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When nauseated, breathe deeply and slowly through your mouth.

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Avoid foods that are high in fat, which tend to remain in the stomach longer than other
foods and may contribute to nausea.

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Chew food well for better digestion.

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Drink liquids well before or after mealtime, instead of during meals. Drink frequently, but drink small amounts.

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Avoid lying flat for at least 2 hours after you finish a meal.

Resources 

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Nausea Shopping List
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About Nausea; it can have other causes  nurseminerva.co.uk  

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New Approaches to Controlling Treatment Side Effects ~ Harold J. Burstein, MD PhD  Medscape 
(free login req.) 
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Cancer Treatment Support: General | Alternative Suggestions | Diet Guidelines
Diet for Immunosuppressed
|
Fight nausea | When to call your doctor

Nausea
Quick Reference
Common side effect of chemotherapy
Can be controlled with drugs and managed with life style changes.
Return to top

 

Research News

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ASCO Updates Guidelines for Use of Antiemetics in Cancer Medscape (free login req.) 2006

"The three-drug regimen is recommended for patients who will be receiving an anthracycline and cyclophosphamide. "It's not that one drug replaces another, you need all three," Dr. Kris emphasized. "It's important that you prescribe them at the get-go." 

Dr. Kris also emphasized that the drugs need to be given for at least two to three days after chemo is completed. "Almost no one gets nausea and vomiting on the day of chemotherapy. That happens a day or two later."

 
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Support Care Cancer. 2012 July; 20(7): 14791489. Ginger Eases Nausea From Chemo PubMed 

Ginger supplementation at daily dose of 0.5g-1.0g significantly aids in reduction of the severity of acute chemotherapy-induced nausea in adult cancer patients.
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New Approaches to Controlling Treatment Side Effects ~ Harold J. Burstein, MD PhD  Medscape (free login req.) 
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FDA Approves New Drug to Combat Nausea and Vomiting for Cancer Patients Getting Chemotherapy  FDA  
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Acupressure for nausea following chemotherapy  Cancer Research
 
Disclaimer:  The information on Lymphomation.org is not intended to be a substitute for 
professional medical advice or to replace your relationship with a physician.
For all medical concerns,  you should always consult your doctor. 
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