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"Venous thrombosis is a condition in which a blood clot (thrombus) forms in a vein. This clot can limit blood flow through the vein, causing swelling and pain. Most commonly, venous thrombosis occurs in the "deep veins" in the legs, thighs, or pelvis. When this occurs, it is called a deep vein thrombosis, or DVT."  - patients.uptodate.com 

Symptomatic thrombosis is much more frequent in cancer patients on chemotherapy than previously estimated, even in patients with hematologic malignancies. ¹

Note: Prolonged periods of immobility, particularly on plane rides and long car trips, can increase risk.

Resources:

Research News

1. [2586] A Predictive Model for Chemotherapy-Associated Thrombosis Based on Findings from a Prospective Outpatient Registry. Session Type: Poster Session 799-II - ASH 2004

2. [1141] Incidence and Risk Factors for Thromboembolism in Patients with Hematologic Malignancies Undergoing Allogeneic and Autologous Stem Cell Transplantation. Session Type: Poster Session 295-I - ASH 2004

3. [4082] The Risk of Deep Venous Thrombosis and Sepsis in Cancer Patients Due to PICC Lines. Session Type: Publication Only - ASH 2004

4. Venous thromboembolism in patients with cancer part I. Survey of oncology nurses' attitudes and treatment practices for ambulatory settings. Clin J Oncol Nurs. 2004 Oct;8(5):455-61. PMID: 15515279