"Three major histopathologic categories:
- small noncleaved cell,
- large cell immunoblastic, plasmacytoid,
- and large noncleaved cell lymphomas.
Approx 90% of AIDS-associated NHLs express B-cell
immunophenotypes including expression of monotypic surface Ig and/or
the B cell-associated antigen CD20 (B1) and absence of T
Approx 10% of AIDS-associated NHLs lack B- and T-cell-lineage
restricted antigens. HIV appears not to be involved directly in the
pathogenesis of AIDS-associated lymphoid neoplasia, because HIV DNA
sequences could not be detected in AIDS-associated lymphoid
EBV, however, may be involved in the pathogenesis of up to one
third of AIDS-associated B-NHLs"