A "leukemic or
is a finding of unusual high amounts of lymphocytes in the
peripheral blood (lymphocytosis) suggesting that the lymphoma cells
are in the blood in high concentrations.
lymphocytosis is an
abnormal increase in the number of lymphocytes — a type of white
blood cell — in your blood. The most common cause is viral
infection, such as EBV, CMV, rubella,
whooping cough, toxoplasmosis, brucellosis, chronic lymphatic
leukaemiam, and leukemic phase lymphoma.
It's our impression that special attention must be
paid to tumor lysis syndrome when treating lymphoma in the leukemic
phase - because the tumor cells may respond very rapidly to
treatment, stressing the body to eliminate the cells killed (lysis)
Leukemic phase of B-cell lymphomas mimicking
chronic lymphocytic leukemia and variants at presentation.
Pathol. 2002 Nov;15(11):1111-20. PMID:
12429788 | Related
Leukemic phase of mantle cell lymphoma,
Am J Clin Pathol. 1999 Apr;111(4):495-500. PMID:
10191769 | Related
FISH analysis for BCL-1 rearrangements and
trisomy 12 helps the diagnosis of atypical B cell leukaemias.
Leukemia. 1999 Nov;13(11):1721-6. PMID:
Blastoid variant of mantle cell lymphoma: late
progression from classical mantle cell lymphoma and quantitation
of minimal residual disease.
Eur J Haematol. 2005 Apr;74(4):353-8. PMID:
15777349 | Related
This report presents a rare case of long-term survivor of MCL
with a progression of the original MCL cell clone to MCL-BV and
demonstrates the clinical value of quantitative minimal residual
disease assessment for optimized therapeutic management.