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Metabolic abnormalities in lymphoma

  

Side Effects > Metabolic abnormalities in lymphoma

Last update: 04/14/2008

Introduction | Resources & Research News

Many lymphoma patients report leg cramping following treatment. Here we list metabolic abnormalities in lymphoma patients undergoing chemotherapy, and links to resources.
 
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The following was adapted from:  Metabolic abnormalities in lymphoma. 
Clin Lymphoma. 2002 Dec;3 Suppl 1:S32-6. PMID: 12521387  PubMed 

Tumor lysis syndrome can result in several metabolic abnormalities, leading to potential renal failure. If these syndromes are identified promptly, they can be corrected. Guidelines for identifying metabolic abnormalities in lymphoma patients, as well as management suggestions, are presented. 

These chemotherapy- and lymphoma-associated metabolic abnormalities include:

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Hyperuricemia - high uric acid levels
Details: www.emedicine.com/med/topic1112.htm 

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Hypercalcemia - high concentrations of calcium compounds are found in the bloodstream.
Details: www.emedicine.com/EMERG/topic260.htm 
A Practical Approach to Hypercalcemia www.aafp.org/afp/20030501/1959.html 

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Hyperphosphatemia - high concentration of phosphates in the circulating blood. 
Details: www.emedicine.com/emerg/topic266.htm 

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Hypocalcemia - abnormally low calcium concentration, that can result in muscle cramps, abdominal cramps, spasms, and hyperactive deep tendon reflexes. 
Details: www.emedicine.com/EMERG/topic271.htm 

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Hypomagnesemia - abnormally low levels of serum mangnesium. "The primary clinical findings are neuromuscular irritability, CNS hyperexcitability, and cardiac arrhythmias."
Details: www.emedicine.com/EMERG/topic274.htm 

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Hyponatremia - abnormally low levels of serum sodium concentration.
Details: www.emedicine.com/EMERG/topic275.htm 

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Hyperkalemia - a potassium level greater than 5.5 mEq/L. Ranges are as follows: 5.5 - 6.0 mEq/L - Mild condition 6.1 - 7.0 mEq/L - Moderate condition 7.0 mEq/L and greater - Severe condition. Details:  www.emedicine.com/emerg/topic261.htm 
   

Related Resources & Research News

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Metabolic emergencies in the cancer patient. Semin Oncol. 2000 Jun;27(3):322-34. Review.
PMID: 10864220  PubMed
 
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For all medical concerns,  you should always consult your doctor. 
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