vedotin has been approved for treatment of relapsed or
refractory Hodgkin lymphoma and anaplastic T cell lymphoma.
The trade name is Adcetris.
Adcetris is a
antibody-drug conjugate that binds to a molecule called cd30
on cells in Hodgkin lymphoma and anaplastic T cell lymphoma -
but also other types of lymphoma at different frequencies or
antibody is linked to a potent toxin, which is released inside
the cell the antibody sticks to.