Treatments or Chemotherapy >
Chemo agents, Alphabetical Index
Last update:
01/31/2010 |
A
| B | C | D | E
| F | G | H | I
| J | K | L | M
| N
O | P | Q
| R | S | T | U
| V | W | X |
Y | Z
Also see Drug
Indexes:
A
 | Adriamycin®, (Doxorubicin, Rubex®)
Druginfo
|
|
Ara-C (Cytarabine, Cytosine Arabinoside, Cytosar) Cancer.gov
|
B
|
 |
Recently approved for CLL ... will likely be available
off-label for other lymphomas based on strong supporting data.
|
|
Treanda (Bendamustine) Full Prescribing information FDA
PDF
|
|
Bendamustine in Patients With Rituximab-Refractory
Indolent and Transformed Non-Hodgkin's Lymphoma: Results From a
Phase II Multicenter, Single-Agent Study http://jco.ascopubs.org/cgi/content/full/26/2/204
|
| Bendamustine (Treanda) For Chronic Lymphocytic Leukemia
A Brief Overview pubmedcentral.nih.gov
|
|
NEW Bendamustine, but not fludarabine, -
low stem cell toxicity in vitro.
http://bit.ly/aOgmrR
|
|
| Bleomycin (Blenoxane®) Cancerbacup
|
|
|
C
| Carboplatin (Paraplatin®)
Cancer.gov
|
|
|
|
|
| Chlorodeoxyadenosine (Cladribine®) MedlinePlus
Other names: 2-chlorodeoxyadenosine; 2-CdA
Cisplatin (Platinol®)
Cancer.gov
|
|
|
Potential Immune-modulating effects of Cytoxan:
PubMed
query |
|
|
Cytarabine (cytosine arabinoside, Ara-C, Cytosar)
cancer.gov
|
D
E
F
G
H
I
| Idarubicin (Idamycin®)
|
| Ifosfamide (ifex®)Lomustine (CCNU®)
DrugInfo.gov
|
J
K
L
|
|
|
Liposomal Doxorubicin (Doxil) chemocare.com
Full prescribing info from Doxil.com PDF
| PDF-Help |
|
Liposomal
vincristine (investigational) (Onco TSC) in relapsed non-Hodgkin's lymphomas: early results of
an ongoing phase II trial.
Ann Oncol. 2000 Jan;11(1):69-72. PMID: 10690390
PubMed
|
Abstracts
|
M
| Mechlorethamine (nitrogen mustard, Mustargen®)
BCCancer
|
| Melphalan (Alkeran®) BCCancer
|
|
Mercaptopurine oral (Purinethol®) BCCancer
|
|
Methotrexate oral (Rheumatrex®) BCCancer
Other name: amethopterin
|
| Methylprednisolone (Medrol®)
Medline
|
|
|
|
Mitoxantrone (Novantrone®) BCCancer
|
N
O
P
| Pentostatin IV (Nipent®)
Cancer.gov
|
| Pixantrone (investigational) (BR 2778):
Alternative to Doxorubicin?
Might have similar activity against
aggressive lymphomas as doxorubicin,
with less cardio toxicity Abstracts
|
Clinical trials
|
|
|
|
Procarbazine (Matulane®) BCCancer
|
R
S
T
|
|
| Thioguanine oral (Lanvis®)
|
| Trofosfamide
(palliative/elderly) as a salvage treatment with low toxicity in
malignant lymphoma.
A phase II study. Eur J Cancer. 1997
Mar;33(3):500-2. PMID: 9155539 PubMed
| Abstracts
|
U
V
|
Vinblastine (Velban®)
|
| Vincristine (Oncovin®) Cancer.gov
NOTE: Adjusting the dose of Vincristine is common due to
variable way individuals metabolize
the drug and differences in half-life.
Clearance of the drug can vary from 23 to 85 hrs for adults;
and from 10 to 40 hrs in children. Source
bccancer.bc.ca
Notify your doctor of
symptoms associated with this drug.
"The neurotoxicity commonly manifests as
... constipation, and peripheral neuropathy which is predominantly
sensory in nature. The early symptoms include numbness and
tingling of hands and feet which is accompanied by loss of deep
tendon reflexes. In its more severe form, muscle weakness develops
which is more marked in distal muscles of the hands and feet.
Other manifestations of neurotoxicity include ocular palsies,
hoarseness of voice, and autonomic neuropathy in the form of
postural hypotension and atony of the urinary bladder. The
neurotoxicity is dose related and cumulative with repeated dosage
such that the drug therapy has to be stopped after a cumulative
dose of 30 to 50 mg. The neurotoxicity is usually reversible on
interruption of the therapy, but the recovery is slow and takes
several months. There are no specific antidotes which have
established usefulness against neurotoxicity." PMID
Predicting toxicity? "Raised level
of serum alkaline phosphatase may predict severe
neurotoxicity" 1
1 Can severe vincristine neurotoxicity be prevented?
Cancer Chemother Pharmacol. 1982;8(2):211-4.
PMID:
6125275 |
Related
Articles
Side effects of
Vincristine, and when to inform your doctor:
Contact your doctor immediately, if
Fever over 100 degrees - indicating possible
infection
Contact your doctor as soon as possible,
if
Lower back or side pain - indicating possible
kidney problems
Swelling of feet or lower legs
Gout-like joint pain
Changes in eye sight, blurry vision, or drooping
eyelid
Trouble walking or climbing stairs
Severe constipation or stomach cramps
Difficulty urinating, or frequent need to
urinate - bed-wetting
Contact your doctor when
needed, if these symptoms continue to bother you
Uncontrolled nausea, vomiting, constipation or
diarrhea
Easy bruising or bleeding
Severe jaw pain or headache
Redness, swelling, pain or sores where the needle was
placed
Redness, swelling, pain or sores on your lips, tongue, mouth or
throat
adapted from BCCancer
|
| Vincristine, liposomal (investigational) (Onco
TSC) in relapsed non-Hodgkin's lymphomas: early results of
an ongoing phase II trial.
Ann Oncol. 2000 Jan;11(1):69-72. PMID: 10690390 PubMed
| Abstracts
|
| Velcade
approved for Multiple Myeloma will be available off label to
patients with NHL Abstracts
|
Background: Managing and avoiding bortezomib
(Velcade) toxicity
Jeffrey Menashe, MD | Northwest Cancer Specialists, Portland, OR
communityoncology.net
pdf
|
|
Dietary flavonoids inhibit the anti-cancer effects of the proteasome inhibitor Bortezomib (Velcade)
Dietary flavonoids, quercetin and myricetin, which are abundant in plasma, inhibited Bortezomib-induced apoptosis of primary CLL and malignant B-cell lines in a dose-dependent manner.
Blood First Edition Paper, pre-published online
July 16, 2008; DOI 10.1182/blood-2008-04-150227.
Sources of flavonoids:
http://lpi.oregonstate.edu/infocenter/phytochemicals/flavonoids/
|
|
|
Vinorelbine (Navelbine®)
FDA
|
Treatment
abstracts
(Vinca alkaloid that interferes with microtubule
assembly)
|
W
X
Y
Z
|
|
Topic
Search