Treatments or Chemotherapy >
Chemo agents, Alphabetical Index
Last update: 03/25/2008 |
A
| B | C | D | E
| F | G | H | I
| J | K | L | M
| N | O | P | Q
| R | S | T | U
| V | W | X |
Y | Z
A
 | Adriamycin®, (Doxorubicin, Rubex®) Cancerbacup
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Ara-C (Cytarabine, Cytosine Arabinoside, Cytosar Cancer.gov
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B
| Bendamustine
(investigational) micromedex.com
> Treatment
abstracts
NEWS:
Recently approved for CLL ... will likely be available
off-label for other lymphomas based on strong supporting data.
Treanda (Bendamustine) Full Prescribing information: FDA
PDF
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| Bleomycin (Blenoxane®) Cancerbacup
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Bexxar PAL
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C
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| Chlorodeoxyadenosine (Cladribine®) MedlinePlus
Other names: 2-chlorodeoxyadenosine; 2-CdA
 |
Evaluation of long-term toxicity in patients after
cisplatin-based chemotherapy for non-seminomatous testicular cancer
PubMed
|
|
| Cyclophosphamide injection (Cytoxan®) Cancer.gov
| Cancerbacup
Cyclophosphamide Metabolism in Children with Non-Hodgkin’s
Lymphoma aacrjournals.org
"Inadequate clearance of cyclophosphamide to active metabolites
is associated with increased risk of recurrence of
B-cell non-Hodgkin’s lymphoma in children. Modified chemotherapy
strategies should be considered in patients who exhibit
low rates of clearance of the parent drug and/or extensive production
of inactive metabolites."
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| Cytarabine (cvtosine
arabinoside, Ara-C, Cytosar) cancer.gov
|
D
E
F
G
H
I
J
K
L
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Liposomal Doxorubicin (Doxil) chemocare.com
Full prescribing info from Doxil.com PDF
| PDF-Help | Cancerbacup
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Liposomal
vincristine (investigational) (Onco TSC) in relapsed non-Hodgkin's lymphomas: early results of
an ongoing phase II trial.
Ann Oncol. 2000 Jan;11(1):69-72. PMID: 10690390 PubMed
| Abstracts
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M
| Mechlorethamine (nitrogen mustard, Mustargen®)
BCCancer
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Methotrexate oral (Rheumatrex®) BBCancer
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Cancerbacup
Other name: amethopterin
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| Methylprednisolone (Medrol®) medline
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N
O
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ONTAK (denileukin diftitox) chemocare.com
- Remission of follicular
non-Hodgkin's lymphoma with denileukin diftitox (ONTAK) after
progression during rituximab, CHOP and fludarabine therapy. Leuk
Lymphoma. 2003 Apr;44(4):731-3. PMID:
12769354 | Abstracts
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P
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| Pixantrone (investigational) (BR 2778):
Alternative to Doxorubicin?
Might have similar activity against
aggressive lymphomas as doxorubicin,
with less cardio toxicity Abstracts
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Clinical trials
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R
S
T
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| Thioguanine oral (Lanvis®) Cancerbacup
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| Trofosfamide
(palliative/elderly) as a salvage treatment with low toxicity in
malignant lymphoma.
A phase II study. Eur J Cancer. 1997
Mar;33(3):500-2. PMID: 9155539 PubMed
| Abstracts
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U
V
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NOTE: Adjusting the dose of Vincristine is common due to
variable way individuals metabolize
the drug and differences in half-life.
Clearance of the drug can vary from 23 to 85 hrs for adults;
and from 10 to 40 hrs in children. Source bccancer.bc.ca
Notify your doctor of
symptoms associated with this drug.
"The neurotoxicity commonly manifests as
... constipation, and peripheral neuropathy which is predominantly
sensory in nature. The early symptoms include numbness and
tingling of hands and feet which is accompanied by loss of deep
tendon reflexes. In its more severe form, muscle weakness develops
which is more marked in distal muscles of the hands and feet.
Other manifestations of neurotoxicity include ocular palsies,
hoarseness of voice, and autonomic neuropathy in the form of
postural hypotension and atony of the urinary bladder. The
neurotoxicity is dose related and cumulative with repeated dosage
such that the drug therapy has to be stopped after a cumulative
dose of 30 to 50 mg. The neurotoxicity is usually reversible on
interruption of the therapy, but the recovery is slow and takes
several months. There are no specific antidotes which have
established usefulness against neurotoxicity." PMID
Predicting toxicity? "Raised level
of serum alkaline phosphatase may predict severe
neurotoxicity" 1
1 Can severe vincristine neurotoxicity be prevented?
Cancer Chemother Pharmacol. 1982;8(2):211-4.
PMID:
6125275 | Related
Articles
Side effects of
Vincristine, and when to inform your doctor:
Contact your doctor immediately, if
Fever over 100 degrees - indicating possible
infection
Contact your doctor as soon as possible,
if
Lower back or side pain - indicating possible
kidney problems
Swelling of feet or lower legs
Gout-like joint pain
Changes in eye sight, blurry vision, or drooping
eyelid
Trouble walking or climbing stairs
Severe constipation or stomach cramps
Difficulty urinating, or frequent need to
urinate - bed-wetting
Contact your doctor when
needed, if these symptoms continue to bother you
Uncontrolled nausea, vomiting, constipation or
diarrhea
Easy bruising or bleeding
Severe jaw pain or headache
Redness, swelling, pain or sores where the needle was
placed
Redness, swelling, pain or sores on your lips, tongue, mouth or
throat
adapted from BBCancer
|
| Vincristine, liposomal (investigational) (Onco
TSC) in relapsed non-Hodgkin's lymphomas: early results of
an ongoing phase II trial.
Ann Oncol. 2000 Jan;11(1):69-72. PMID: 10690390 PubMed
| Abstracts
|
| Velcade
approved for Multiple Myeloma will be available off label to
patients with NHL Abstracts
|
|
Vinorelbine (Navelbine®) FDA
| Treatment
abstracts
(Vinca alkaloid that interferes with microtubule
assembly)
|
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